![]() The team concluded that in China, human-to-human transmission of the virus occurred largely within households. It gave an overview of the trip, assessed the response to the epidemic and identified next steps for China and other countries to take. The report was compiled by a team of more than two dozen specialists from China and overseas who were part of a nine-day WHO trip to Beijing, and Guangdong, Sichuan and Hubei provinces from February 16. Without identifying that animal chain, there was a risk that outbreaks could recur in areas where they had receded, the UN health agency warned. Bats appeared to be the reservoir of the virus, but the intermediate host had not yet been identified. It also said that epidemiologists were convinced that the coronavirus that caused the disease now known as Covid-19 was caused by an organism spread from animals. In a report, also released on Friday, the WHO said it was convinced that China's containment measures were effective as the number of new cases had continued to fall. More cases have also been reported in South Korea, Italy and Iran, prompting the US Centres for Disease Control and Prevention to raise its travel advisory for Italy and Iran, recommending travellers avoid all non-essential trips to those countries due to "limited access to adequate medical care in affected areas". Mainland China has 79,251 infections, with 39,002 patients recovered. So far, the epidemic has killed 2,835 people on the mainland, with 47 more fatalities on Saturday. The study was co-authored by dozens of medical experts, including Dr Zhong Nanshan, director of China's State Key Laboratory of Respiratory Diseases, and Chinese University of Hong Kong respiratory medicine expert Professor David Hui Shu-cheong. "Some patients with Covid-19 do not have fever or radiologic abnormalities on initial presentation, which has complicated the diagnosis," the study said, referring to the disease caused by the coronavirus. ![]() But 88.7 per cent of them did develop one after admission. They found that more than half the patients did not have a fever when they went into hospital, making diagnosis more difficult. In a joint study published in the New England Journal of Medicine, researchers from mainland China and Hong Kong reviewed the cases of 1,099 coronavirus patients from 552 hospitals in 30 provinces. The alerts came on Friday (Feb 28) as the WHO declared that the risk of global spread of the coronavirus epidemic had become "very high" - though the UN health agency stopped short of calling it a pandemic. The findings of the review may be useful to researchers, policymakers, and clinicians caring for people following Covid-19 infection.HONG KONG - Health experts have highlighted challenges with the Covid-19 coronavirus epidemic, with the World Health Organization (WHO) warning of the risk of outbreaks coming back to life and researchers in mainland China and Hong Kong pointing out a major difficulty with diagnosis. The long-term impact of Covid-19 is still in its initial stage. There was disproportional impact on patients by gender, age, severity of illness and study country. The impact of Covid-19 on HRQoL of Acute and Long Covid patients is substantial. Higher impact on HRQoL was reported in Acute Covid, females, older ages, patients with more severe disease and patients from low-income countries. The impact of Covid-19 on HRQoL was found to be considerable in both Acute Covid and Long Covid patients. The majority of the studies used a generic HRQoL assessment tool five studies used SF-36, five studies used EQ-5D-5L, and three used pulmonary disease-specific HRQoL tools (two studies used two tools each). After reading full-text, 12 eligible studies were included in this review. Of these, 77 studies were selected for full-text reading after screening the studies. In total, 1276 studies were identified through the search strategy. Data were synthesised, analysed descriptively and reported in line with PRISMA guidelines. The studies were screened by two reviewers according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) flowchart using pre-determined eligibility criteria. We also explored literature on websites of distinguished public health organisations and hand-searched reference lists of eligible studies. We searched for original studies published between December 2019 and Jan 2021 in PubMed, Scopus and Medline databases using a specific search strategy. However, less attention has been given to its impact on health-related quality of life (HRQoL) of patients with Covid-19. The majority of research into Covid-19 has focused on transmission, and mortality and morbidity associated with the virus. ![]() Coronavirus disease (Covid-19) has led to a global pandemic since its emergence in December 2019.
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